SCHEMBL8962062

SCHEMBL8962062

CCCCCC(C)(C)c1ccc(Nc2ccc(Cc3ccc(Nc4ccc(C(C)(C)CCCCC)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.39
CNR1 P21554 12/20 0.37
GPR55 Q9Y2T6 4/20 0.37
GPR18 Q14330 3/20 0.37
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
EP300 Q09472 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38590 0.82 CDC25B (0.50) CNR2CNR1KDM4EMEN1GLA
SCHEMBL8962170 0.82 SHBG (0.39) CNR1KDM4EMEN1GLAGAA
SCHEMBL3766930 0.81 CDC25B (0.49) CNR2CNR1KDM4EMEN1GLA
SCHEMBL11800783 0.79 MEN1 (0.36) CNR2CNR1KDM4EMEN1GLA
SCHEMBL501958 0.78 CNR2 (0.49) CNR2CNR1MEN1GAAMAPT
SCHEMBL39060 0.78 CNR2 (0.54) CNR2CNR1
SCHEMBL8746945 0.78 CNR2 (0.43) CNR2CNR1
SCHEMBL10699000 0.76 CNR2 (0.46) CNR2CNR1
SCHEMBL10181058 0.75 CNR2 (0.47) CNR2CNR1
SCHEMBL30108338 0.73 MAPT (0.46) CNR2CNR1MEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP claimed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US claimed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP claimed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US claimed
JP-5194331-A None JP disclosed
EP-2791292-B1 CROSS PRODUCTS AND CO-OLIGOMERS OF PHENYLENEDIAMINES AND AROMATIC AMINES AS ANTIOXIDANTS FOR LUBRICANTS LANXESS SOLUTIONS US INC (US) 2018-07-04 EP disclosed
US-8987515-B2 Cross products and co-oligomers of phenylenediamines and aromatic amines as antioxidants for lubricants CHEMTURA CORPORATION (US) 2015-03-24 US disclosed
EP-2791292-A1 CROSS PRODUCTS AND CO-OLIGOMERS OF PHENYLENEDIAMINES AND AROMATIC AMINES AS ANTIOXIDANTS FOR LUBRICANTS Chemtura Corporation (US) 2014-10-22 EP disclosed
WO-2013090051-A1 CROSS PRODUCTS AND CO-OLIGOMERS OF PHENYLENEDIAMINES AND AROMATIC AMINES AS ANTIOXIDANTS FOR LUBRICANTS CHEMTURA CORPORATION (US) 2013-06-20 WO disclosed
US-20130150275-A1 Cross Products and Co-Oligomers of Phenylenediamines and Aromatic Amines as Antioxidants for Lubricants CHEMTURA CORPORATION (US) 2013-06-13 US disclosed
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
JP-H05194331-A SUBSTITUTED 1-AMINONAPHTHALENE AND STABILIZED COMPOSITION CIBA GEIGY AG 1993-08-03 JP disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed