SCHEMBL8962170

SCHEMBL8962170

CC(C)(C)CC(C)(C)c1ccc(Nc2ccc(Cc3ccc(Nc4ccc(C(C)(C)CC(C)(C)C)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.39
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
MAPT P10636 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 5/20 0.35
CYP3A4 P08684 5/20 0.35
TP53 P04637 4/20 0.35
USP2 O75604 3/20 0.35
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
SLC6A3 Q01959 3/20 0.35
KCNH2 Q12809 3/20 0.35
ESR1 P03372 2/20 0.35
PGR P06401 2/20 0.35
ADORA3 P0DMS8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962062 0.82 CNR2 (0.39) MEN1KMT2AMAPTTDP1GAA
SCHEMBL38589 0.80 CDC25B (0.56) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL29387958 0.80 CDC25B (0.56) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL8373131 0.78 ALDH1A1 (0.61) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL11805330 0.77 MEN1 (0.40) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL11805334 0.77 MEN1 (0.40) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL8962065 0.77 GAA (0.63) MEN1KMT2AMAPTTDP1GAA
SCHEMBL8962181 0.75 SHBG (0.52) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL411772 0.75 SHBG (0.59) SHBGMEN1KMT2AMAPTTDP1
SCHEMBL11130087 0.74 CDC25B (0.51) SHBGMEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP claimed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US claimed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP claimed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US claimed
EP-2791292-B1 CROSS PRODUCTS AND CO-OLIGOMERS OF PHENYLENEDIAMINES AND AROMATIC AMINES AS ANTIOXIDANTS FOR LUBRICANTS LANXESS SOLUTIONS US INC (US) 2018-07-04 EP disclosed
US-8987515-B2 Cross products and co-oligomers of phenylenediamines and aromatic amines as antioxidants for lubricants CHEMTURA CORPORATION (US) 2015-03-24 US disclosed
US-20130150275-A1 Cross Products and Co-Oligomers of Phenylenediamines and Aromatic Amines as Antioxidants for Lubricants CHEMTURA CORPORATION (US) 2013-06-13 US disclosed
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed