Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | CDC25A | P30304 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738538 | 0.84 | CYP2C19 (0.64) | HSD17B10POLBCYP2C19KDM4EAKR1C3 | |
| SCHEMBL2047090 | 0.82 | CYP2C19 (0.66) | POLBCYP2C19L3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL11423645 | 0.82 | POLB (0.54) | CDC25BHSD17B10CDC25APOLBKDM4E | |
| SCHEMBL2890963 | 0.81 | KDM4E (0.65) | HSD17B10POLBCYP2C19KDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL28386079 | 0.81 | CYP2C19 (0.64) | POLBCYP2C19L3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL17342844 | 0.81 | TERT (0.56) | POLBCYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL3074652 | 0.81 | CDC25B (1.00) | CDC25BHSD17B10CDC25APOLBKDM4E | |
| SCHEMBL110042 | 0.81 | POLB (0.72) | HSD17B10POLBCYP2C19KDM4EALDH1A1 | |
| SCHEMBL29437050 | 0.81 | POLB (0.72) | HSD17B10POLBCYP2C19KDM4EALDH1A1 | |
| SCHEMBL2058645 | 0.81 | CDC25B (1.00) | CDC25BHSD17B10CDC25APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |