Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423645 | 0.87 | POLB (0.54) | KDM4EHSD17B10AKR1C3AKR1C2TDP1 | |
| SCHEMBL14434162 | 0.85 | ALDH1A1 (0.60) | TDP1L3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL7012306 | 0.82 | NEU3 (0.56) | KDM4EHSD17B10AKR1C3AKR1C2POLB | |
| SCHEMBL8533041 | 0.81 | KDM4E (0.69) | KDM4EHSD17B10TDP1POLBALDH1A1 | |
| SCHEMBL31451940 | 0.81 | KDM4E (0.69) | KDM4EHSD17B10TDP1POLBALDH1A1 | |
| SCHEMBL8962183 | 0.81 | CDC25B (0.66) | KDM4EHSD17B10AKR1C3AKR1C2TDP1 | |
| SCHEMBL11803827 | 0.80 | KDM4E (0.67) | KDM4EHSD17B10AKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL7001348 | 0.80 | KDM4E (0.67) | KDM4EHSD17B10AKR1C3AKR1C2TDP1 | |
| SCHEMBL111313 | 0.79 | ALDH1A1 (0.76) | KDM4EHSD17B10AKR1C3AKR1C2TDP1 | |
| SCHEMBL5098575 | 0.79 | KDM4E (0.65) | KDM4EHSD17B10TDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2011-12-01 | — | — | US | disclosed |
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | 2010-11-11 | — | — | US | disclosed |
| EP-2185504-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2010029300-A1 | BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |
| WO-2009030887-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | KDM4E 3299/4885HSD17B10 941/4885AKR1C3 74/4885 |
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | LTC4S, LTB4R2, LTB4R | KDM4E 3526/4885HSD17B10 1159/4885AKR1C3 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.