SCHEMBL8962222

SCHEMBL8962222

CCCCOc1ccccc1C(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.59
CDC25B P30305 1/20 0.59
HSD17B10 Q99714 1/20 0.59
LMNA P02545 2/20 0.56
PTPN11 Q06124 4/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
NR1I2 O75469 1/20 0.50
CHRM2 P08172 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
MAPT P10636 1/20 0.50
OPRK1 P41145 1/20 0.50
HTR2B P41595 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
ALDH1A1 P00352 4/20 0.49
PTK2B Q14289 1/20 0.49
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962412 0.88 LMNA (0.72) CDC25ACDC25BHSD17B10LMNAKMT2A
SCHEMBL18917587 0.84 DRD2 (0.59) LMNAKMT2AMEN1NR1I2CHRM2
SCHEMBL29518968 0.84 DRD2 (0.59) LMNAKMT2AMEN1NR1I2CHRM2
Bicarbonate SCHEMBL28775865 0.83 DRD2 (0.58) LMNAKMT2AMEN1NR1I2CHRM2
SCHEMBL301123 0.83 KMT2A (0.69) HSD17B10LMNAPTPN11KMT2AMEN1
Benzene SCHEMBL28006345 0.83 KMT2A (0.69) HSD17B10LMNAPTPN11KMT2AMEN1
SCHEMBL29994009 0.83 KMT2A (0.69) HSD17B10LMNAPTPN11KMT2AMEN1
SCHEMBL257257 0.82 LMNA (0.54) CDC25ACDC25BHSD17B10LMNAPTPN11
SCHEMBL3864160 0.81 KMT2A (0.67) HSD17B10LMNAPTPN11KMT2AMEN1
Bicarbonate SCHEMBL20694840 0.81 KMT2A (0.67) HSD17B10LMNAPTPN11KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5530130-A DYEING PLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed
EP-0639624-A1 Phthaloperinone dyestuffs BAYER AG (DE) 1995-02-22 EP disclosed
US-3932419-A QUINOLINE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed