Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967447 | 0.87 | PIK3R1 (0.35) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL2966766 | 0.87 | PIK3R1 (0.35) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL8962241 | 0.87 | GAA (0.36) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL2964510 | 0.73 | PIK3R1 (0.32) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL2975318 | 0.73 | TDP2 (0.34) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL8962211 | 0.72 | MEN1 (0.40) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2971181 | 0.69 | PIK3R1 (0.35) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2973396 | 0.69 | PIK3R1 (0.35) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29317368 | 0.67 | POLB (0.41) | HTR1AHTR7POLBKDM4EMEN1 | |
| SCHEMBL2970796 | 0.66 | PIK3R1 (0.37) | POLBKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |