Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962344 | 0.72 | HTR1A (0.35) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL7756242 | 0.68 | PARP10 (0.33) | ALDH1A1HSD17B10HPGDMAPK1ALOX5 | |
| SCHEMBL8962241 | 0.68 | GAA (0.36) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2966766 | 0.68 | PIK3R1 (0.35) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2967447 | 0.65 | PIK3R1 (0.35) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2973597 | 0.65 | MAOA (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL2969646 | 0.65 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL29755699 | 0.64 | KDM4E (0.51) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL7116127 | 0.64 | KDM4E (0.51) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL22411732 | 0.64 | NLRP3 (0.36) | MEN1KMT2AALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |