Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962531 | 0.87 | SMN1; SMN2 (0.47) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8962536 | 0.86 | SOAT1 (0.44) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9390816 | 0.86 | SMN1; SMN2 (0.50) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8962535 | 0.84 | SMN1; SMN2 (0.60) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8962404 | 0.83 | FABP3 (0.46) | — | |
| SCHEMBL8962425 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL8962550 | 0.81 | NLRP3 (0.58) | — | |
| SCHEMBL8962577 | 0.81 | TSHR (0.46) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8962491 | 0.79 | KMT2A (0.58) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9059980 | 0.78 | LMNA (0.45) | LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5239082-A | Sulfonamide tetrazole ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-08-24 | — | — | US | disclosed |