Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912877 | 1.00 | LIPG (0.44) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL6913106 | 0.93 | LIPG (0.35) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL28332685 | 0.83 | KCNH2 (0.37) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL27462816 | 0.83 | KCNH2 (0.37) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL6912710 | 0.79 | GABRA1 (0.40) | CYP2D6 | |
| SCHEMBL28603372 | 0.79 | NR1H2 (0.40) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL2965292 | 0.78 | TYR (0.37) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL8662756 | 0.78 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL27629531 | 0.76 | LIPG (0.39) | LIPGBIDMCL1PPARABCL2L1 | |
| SCHEMBL2959429 | 0.76 | TYR (0.35) | LIPGCYSLTR2CYSLTR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |