Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962541 | 0.76 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962485 | 0.76 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962495 | 0.76 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962356 | 0.76 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962520 | 0.76 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962453 | 0.74 | MAPT (0.42) | KDM4ESOAT1MAPT | |
| SCHEMBL8962396 | 0.73 | KMT2A (0.43) | KMT2ASOAT1TRPV1 | |
| SCHEMBL8962772 | 0.71 | SOAT1 (0.46) | SOAT1 | |
| SCHEMBL856209 | 0.69 | CYP3A4 (0.57) | KMT2APKM | |
| SCHEMBL9321851 | 0.67 | KMT2A (0.55) | KMT2AALDH1A1POLBPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | claimed |