Biphenyl

Biphenyl

SCHEMBL8962449

O=C(O)C1CCCCC1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.61
NPC1 O15118 1/20 0.61
HPGD P15428 1/20 0.53
FASN P49327 1/20 0.50
ADORA1 P30542 3/20 0.49
LMNA P02545 2/20 0.49
PTPN1 P18031 1/20 0.48
ADORA2A P29274 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C1 Q04828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL11881576 0.89 RAB9A (0.74) RAB9ANPC1ADORA1LMNAADORA2A
Biphenyl SCHEMBL7611759 0.89 RAB9A (0.74) RAB9ANPC1ADORA1LMNAADORA2A
Biphenyl SCHEMBL958818 0.87 HPGD (0.53) RAB9ANPC1HPGDFASNADORA1
Benzene SCHEMBL30877927 0.86 CES2 (0.55) RAB9ANPC1HPGDLMNAALDH1A1
Benzene SCHEMBL9226365 0.86 CES2 (0.55) RAB9ANPC1HPGDLMNAALDH1A1
Benzene SCHEMBL30877920 0.86 CES2 (0.55) RAB9ANPC1HPGDLMNAALDH1A1
Catechol SCHEMBL10571606 0.85 HPGD (0.52) RAB9ANPC1HPGDLMNAALDH1A1
Biphenyl SCHEMBL7615710 0.85 RAB9A (0.55) RAB9ANPC1HPGDFASNADORA1
Benzoic Acid SCHEMBL31356467 0.83 SRD5A2 (0.58) RAB9ANPC1HPGDALDH1A1KMT2A
Benzene SCHEMBL9232305 0.83 TSHR (0.50) RAB9ANPC1HPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471277-B1 Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEM RES (JP) 1995-11-15 EP claimed
US-5329034-A Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-07-12 US claimed
EP-0471277-A2 Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-02-19 EP claimed
US-5026505-A Pleochroic dyes with trans=4=substituted cyclohexyl groups; improved display contrast stability HITACHI, LTD. (JP) 1991-06-25 US claimed
EP-0429662-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT MITSUBISHI KASEI CORPORATION (JP) 1991-06-05 EP claimed
US-4778619-A Liquid crystal compositions MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1988-10-18 US claimed
US-4733949-A LOW TEMPERATURE RESPONSE TIME HITACHI, LTD. (JP) 1988-03-29 US claimed
EP-2117526-B1 INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE 1 ENZYME ABBOTT LAB (US) 2013-04-03 EP disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed
EP-0471277-B1 Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEM RES (JP) 1995-11-15 EP disclosed
US-5357357-A Liquid crystal display devices with organic thin film formed by compressing molecules on liquid surface and transferring to substrate by horizontal lifting HITACHI, LTD. (JP) 1994-10-18 US disclosed
US-5329034-A Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-07-12 US disclosed
EP-0133182-A1 OXIDATION-REDUCTION COLOR PRODUCTION-TYPE HEAT-SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-02-20 EP disclosed
US-4495083-A PLEOCHROIC, ANTHRAQUINONE DYE HITACHI, LTD. (JP) 1985-01-22 US disclosed
US-4493532-A Pleochroic azo dyes, a liquid crystal composition containing the azo dyes and a display device using the liquid crystal composition HITACHI, LTD. (JP) 1985-01-15 US disclosed
US-4483593-A ANTHRAQUINONE DYES, MULITICOLOR HITACHI, LTD. (JP) 1984-11-20 US disclosed
US-4454057-A CONTAINING PERYLENE DYE HITACHI LTD. (JP) 1984-06-12 US disclosed
US-4434072-A PLEOCHROIC ANTHRAQUINONE DYE MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1984-02-28 US disclosed
US-4324455-A CONTAINING A QUINOPHTHALONE DYE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1982-04-13 US disclosed