SCHEMBL8962474

SCHEMBL8962474

C=C(F)C(=O)OCCC[Si](C)(C)Cl

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962659 0.89 THRB (0.32) TSHRTHRB
SCHEMBL8962358 0.84 TSHR (0.38) TSHRTHRB
SCHEMBL692374 0.84 TSHR (0.55) TSHRTHRB
SCHEMBL8962506 0.81 TSHR (0.40) TSHRTHRB
SCHEMBL9641010 0.79 TSHR (0.37) TSHRTHRB
SCHEMBL8962565 0.79 TSHR (0.58) TSHRTHRB
Hexane SCHEMBL28941486 0.78 TSHR (0.67) TSHRTHRB
SCHEMBL8962614 0.78 TSHR (0.51) TSHR
SCHEMBL23321855 0.77 TSHR (0.61) TSHRTHRB
SCHEMBL23321741 0.77 TSHR (0.61) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed