SCHEMBL8962625

SCHEMBL8962625

Oc1ccccc1-c1ccc(Cc2ccccc2)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.42
TXNRD1 Q16881 1/20 0.42
NOX4 Q9NPH5 1/20 0.42
ALOX15 P16050 1/20 0.41
IDO1 P14902 2/20 0.41
BCL2L1 Q07817 2/20 0.40
BCL2 P10415 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
IDH1 O75874 1/20 0.38
AOC3 Q16853 1/20 0.38
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019421 0.81 PKM (0.49) ALOX15IDO1ALDH1A1HPGDHSD17B10
SCHEMBL8962806 0.77 IDO1 (0.56) ALOX15IDO1BCL2L1ALDH1A1HPGD
SCHEMBL4491047 0.76 CYP1A2 (0.53) HPGDHSD17B10AOC3CCNB2CDK1
SCHEMBL890971 0.74 CALM1 (0.58) BCL2L1BCL2HPGDHCAR2AOC3
SCHEMBL8962646 0.72 HSD17B10 (0.58) CHUKTXNRD1NOX4ALOX15IDO1
SCHEMBL8963081 0.71 PIM1 (0.50) CHUKTXNRD1NOX4ALOX15BCL2L1
SCHEMBL11351970 0.68 BCL2L1 (0.64) CHUKTXNRD1NOX4BCL2L1BCL2
SCHEMBL8056666 0.68 BCL2L1 (0.57) CHUKTXNRD1NOX4ALOX15BCL2L1
SCHEMBL8962876 0.68 IDO1 (0.47) ALOX15IDO1BCL2L1ALDH1A1HPGD
SCHEMBL21686770 0.68 HPGD (0.47) ALOX15IDO1BCL2L1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543286-A CONTAINING AN ORGANIC SILVER SALT AND A PYRROLE COMPOUND;HIGH CONTRAST IMAGES CANON KABUSHIKI KAISHA (JP) 1996-08-06 US disclosed