Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.34 |
| ▸ | PDE2A | O00408 | 8/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963026 | 0.96 | EPHX2 (0.36) | EPHX2PDE2AS1PR1 | |
| SCHEMBL8963018 | 0.96 | EPHX2 (0.36) | EPHX2PDE2AS1PR1 | |
| SCHEMBL9543549 | 0.90 | KDM1A (0.39) | EPHX2PDE2A | |
| SCHEMBL8963176 | 0.87 | CTSK (0.37) | EPHX2PDE2AS1PR1 | |
| SCHEMBL8963179 | 0.87 | CTSK (0.37) | EPHX2PDE2AS1PR1 | |
| SCHEMBL8835502 | 0.86 | PDE2A (0.33) | EPHX2PDE2AFFAR4 | |
| SCHEMBL8835498 | 0.86 | PDE2A (0.33) | EPHX2PDE2AFFAR4 | |
| SCHEMBL23666201 | 0.85 | EPHX2 (0.35) | EPHX2PDE2AFFAR4 | |
| SCHEMBL12975898 | 0.84 | EPHX2 (0.35) | EPHX2PDE2AFFAR4S1PR1 | |
| SCHEMBL8452143 | 0.84 | EPHX2 (0.32) | EPHX2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |