Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | PDE2A | O00408 | 5/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963026 | 0.93 | EPHX2 (0.36) | KDM1AEPHX2PDE2A | |
| SCHEMBL8963018 | 0.93 | EPHX2 (0.36) | KDM1AEPHX2PDE2A | |
| SCHEMBL8962943 | 0.90 | EPHX2 (0.34) | EPHX2PDE2A | |
| SCHEMBL8962822 | 0.89 | KDM1A (0.47) | KDM1AHTR2APDE2ARXRAGRIN1 | |
| SCHEMBL8962830 | 0.89 | KDM1A (0.47) | KDM1AHTR2APDE2ARXRAGRIN1 | |
| SCHEMBL8962898 | 0.86 | KDM1A (0.43) | KDM1AHTR2APDE2ARXRAGRIN1 | |
| SCHEMBL8963179 | 0.84 | CTSK (0.37) | EPHX2PDE2AGRIN2B | |
| SCHEMBL8963176 | 0.84 | CTSK (0.37) | EPHX2PDE2AGRIN2B | |
| SCHEMBL12997536 | 0.80 | EPHX2 (0.45) | KDM1AEPHX2PDE2A | |
| SCHEMBL8963103 | 0.80 | KIF11 (0.46) | KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |