Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707078 | 0.92 | ESR2 (0.65) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL918552 | 0.87 | ESR1 (0.48) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL3416033 | 0.87 | ESR1 (0.48) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL918042 | 0.87 | ESR1 (0.48) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL15224663 | 0.86 | ESR1 (0.47) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| Phenol SCHEMBL8634617 | 0.81 | ESR1 (0.83) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| Phenol SCHEMBL29040626 | 0.81 | ESR1 (0.83) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| Phenol SCHEMBL28975544 | 0.79 | LTA4H (0.52) | ESR1ESR2LTA4HNR1H2BAX | |
| Phenol SCHEMBL29118790 | 0.79 | ESR1 (0.72) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| Phenol SCHEMBL8963230 | 0.79 | ESR1 (0.50) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563237-A | INCLUDES A BISMALEIMIDE HARDENER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-08 | — | — | US | disclosed |