Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416033 | 1.00 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL918552 | 1.00 | ESR1 (0.48) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL15224663 | 0.98 | ESR1 (0.47) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL11707078 | 0.92 | ESR2 (0.65) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| Phenol SCHEMBL8962972 | 0.87 | ESR1 (0.54) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL25873083 | 0.85 | ESR1 (0.37) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL12908790 | 0.85 | ESR1 (0.37) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL9244667 | 0.78 | PNMT (0.34) | ALDH1A1 | |
| SCHEMBL22966325 | 0.74 | MEN1 (0.37) | ALDH1A1L3MBTL1LMNAMAPTBACE1 | |
| SCHEMBL10086337 | 0.74 | SLC6A4 (0.58) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265570-B1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-25 | — | — | EP | claimed |
| US-9045394-B2 | Aromatic dicyanate compounds with high aliphatic carbon content | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-06-02 | — | — | US | claimed |
| US-20110009559-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-01-13 | — | — | US | claimed |
| EP-2265570-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | Dow Global Technologies Inc. (US) | 2010-12-29 | — | — | EP | claimed |
| WO-2009114465-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-09-17 | — | — | WO | claimed |
| EP-2265570-B1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-25 | — | — | EP | disclosed |
| US-9169352-B2 | Aromatic dicyanate compounds with high aliphatic carbon content | BLUE CUBE IP LLC (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150166727-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | BLUE CUBE IP LLC | 2015-06-18 | — | — | US | disclosed |
| US-9045394-B2 | Aromatic dicyanate compounds with high aliphatic carbon content | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-8729181-B2 | Aromatic polycyanate compounds and process for the production thereof | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-05-20 | — | — | US | disclosed |
| US-20110009562-A1 | AROMATIC POLYCYANATE COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009559-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265570-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | Dow Global Technologies Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-2254928-A1 | AROMATIC POLYCYANATE COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | Dow Global Technologies Inc. (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009114465-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009114469-A1 | AROMATIC POLYCYANATE COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009562-A1 | AROMATIC POLYCYANATE COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | PAH, TYR, ARNT | ESR1 4336/4885ESR2 4313/4885ALDH1A1 3631/4885 |
| US-20110009559-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | CCDC6, WDR48, MCCC2 | ESR1 1157/4885ESR2 1655/4885ALDH1A1 2592/4885 |
| US-20150166727-A1 | AROMATIC DICYANATE COMPOUNDS WITH HIGH ALIPHATIC CARBON CONTENT | CCDC6, WDR48, MCCC2 | ESR1 1157/4885ESR2 1655/4885ALDH1A1 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.