Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962853 | 0.85 | PDE2A (0.36) | PDE2APDE10A | |
| SCHEMBL8963223 | 0.81 | PDE2A (0.35) | PDE2APDE10A | |
| SCHEMBL8963217 | 0.81 | PDE2A (0.35) | PDE2APDE10A | |
| SCHEMBL7779309 | 0.76 | — | — | |
| SCHEMBL7779313 | 0.76 | — | — | |
| SCHEMBL8963104 | 0.75 | JAK2 (0.34) | PDE2APDE10A | |
| SCHEMBL8963112 | 0.75 | JAK2 (0.34) | PDE2APDE10A | |
| SCHEMBL7774379 | 0.74 | KDM1A (0.31) | — | |
| SCHEMBL7774376 | 0.74 | KDM1A (0.31) | — | |
| SCHEMBL14264392 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0559860-A1 | HALOVINYL-DERIVATIVES. | HOFFMANN LA ROCHE (CH) | 1993-09-15 | — | — | EP | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |