Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963223 | 0.96 | PDE2A (0.35) | PDE2APDE10AMGLL | |
| SCHEMBL8963217 | 0.96 | PDE2A (0.35) | PDE2APDE10AMGLL | |
| SCHEMBL8963104 | 0.87 | JAK2 (0.34) | PDE2APDE10A | |
| SCHEMBL8963112 | 0.87 | JAK2 (0.34) | PDE2APDE10A | |
| SCHEMBL8963152 | 0.85 | PDE2A (0.31) | PDE2APDE10A | |
| SCHEMBL8451380 | 0.85 | PDE2A (0.31) | PDE2APDE10AMGLL | |
| SCHEMBL8451384 | 0.85 | PDE2A (0.31) | PDE2APDE10AMGLL | |
| SCHEMBL8963038 | 0.84 | — | — | |
| SCHEMBL8767140 | 0.83 | PDE4B (0.37) | PDE2APDE10AMGLL | |
| SCHEMBL8962943 | 0.83 | EPHX2 (0.34) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |