Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963247 | 1.00 | GPR84 (0.37) | GPR84MAOBERN1PTGS2HTR6 | |
| SCHEMBL8727250 | 0.88 | GPR84 (0.38) | GPR84MAOBERN1PTGS2HTR6 | |
| SCHEMBL8727245 | 0.88 | GPR84 (0.38) | GPR84MAOBERN1PTGS2HTR6 | |
| SCHEMBL8727240 | 0.88 | GPR84 (0.38) | GPR84MAOBERN1PTGS2HTR6 | |
| SCHEMBL8727235 | 0.88 | GPR84 (0.38) | GPR84MAOBERN1PTGS2HTR6 | |
| SCHEMBL8963063 | 0.87 | MAOB (0.47) | MAOB | |
| SCHEMBL8963071 | 0.87 | MAOB (0.47) | MAOB | |
| SCHEMBL8963138 | 0.85 | MAOB (0.44) | GPR84MAOBMAOA | |
| SCHEMBL8963130 | 0.85 | MAOB (0.44) | GPR84MAOBMAOA | |
| SCHEMBL8963269 | 0.85 | MAOB (0.44) | GPR84MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |