Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963063 | 1.00 | MAOB (0.47) | MAOBKCNH2TAAR1 | |
| SCHEMBL9543545 | 0.93 | MAOB (0.42) | MAOBKCNH2 | |
| SCHEMBL8963096 | 0.87 | GRM2 (0.39) | MAOBKCNH2 | |
| SCHEMBL8963087 | 0.87 | GRM2 (0.39) | MAOBKCNH2 | |
| SCHEMBL8963245 | 0.87 | GPR84 (0.37) | MAOB | |
| SCHEMBL8963247 | 0.87 | GPR84 (0.37) | MAOB | |
| SCHEMBL8962937 | 0.85 | LMNA (0.39) | KCNH2 | |
| SCHEMBL8962942 | 0.85 | LMNA (0.39) | KCNH2 | |
| SCHEMBL8963138 | 0.85 | MAOB (0.44) | MAOB | |
| SCHEMBL8963277 | 0.85 | MAOB (0.44) | MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0559860-A1 | HALOVINYL-DERIVATIVES. | HOFFMANN LA ROCHE (CH) | 1993-09-15 | — | — | EP | disclosed |