SCHEMBL8963285

SCHEMBL8963285

CCc1ccc(CC)c(P)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KIF11 P52732 1/20 0.38
CA2 P00918 1/20 0.35
TP53 P04637 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
BACE1 P56817 1/20 0.34
AKR1C3 P42330 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13522277 0.90 NPC1 (0.39) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL8963545 0.81 TRPA1 (0.43) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL444673 0.77 TRPA1 (0.48) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL6632297 0.76 TRPA1 (0.43) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL15355003 0.76 TRPA1 (0.43) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL24165348 0.74 MAPT (0.37) ALDH1A1LMNAMAPTMAPK1SMN1; SMN2
SCHEMBL16373580 0.74 TRPA1 (0.41) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL10306733 0.74 HSD17B3 (0.46) TRPA1ALDH1A1MAPTTP53
SCHEMBL394899 0.73 NOS3 (0.45) TRPA1CYP1A2CYP2A6ALDH1A1NPC1
SCHEMBL5050079 0.73 TRPA1 (0.44) TRPA1CYP1A2CYP2A6ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100549092-C Flame retardant epoxy prepregs, laminates, and printed wiring boards with enhanced thermal stability ALBEMARLE CORP (US) 2009-10-14 CN disclosed
CN-1871300-A Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability ALBEMARLE CORP (US) 2006-11-29 CN disclosed
US-5481049-A REACTING CONJUGATED DIENE AND WATER IN PRESENCE OF CARBON DIOXIDE, USING PALLADIUM COMPOUND AND A FREE PHOSPHINE AS CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-02 US disclosed
CN-1096286-A The method for preparing the alkadiene alcohol compound MITSUBISHI CHEM IND (JP) 1994-12-14 CN disclosed