Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352588 | 0.78 | KDM4E (0.42) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL542873 | 0.76 | KDM4E (0.50) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL3104291 | 0.76 | KDM4E (0.41) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL3364531 | 0.76 | KDM4E (0.41) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL997422 | 0.74 | LMNA (0.46) | KDM4EMTNR1AMTNR1BLMNASLC6A4 | |
| SCHEMBL9316517 | 0.72 | MTNR1A (0.40) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL4924896 | 0.72 | HCAR2 (0.41) | LMNAADRA2AADRA2BADRA2C | |
| SCHEMBL9296320 | 0.72 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| SCHEMBL29159322 | 0.72 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BLMNAPOLB | |
| Methylamine SCHEMBL10763289 | 0.72 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560751-A | CYCLIZATION OF AMIDO-THIOAMIDE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | claimed |
| US-4167394-A | MONOAZO DYES HAVING INDOLE OR PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1979-09-11 | — | — | US | claimed |
| EP-0463995-B1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| US-5196521-A | Colorfastness; red; polyesters | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0463995-A1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| EP-0100018-B1 | PROCESS FOR THE PRODUCTION OF 2-N,N-DISUBSTITUTED AMINOTHIAZOLES | BASF Aktiengesellschaft (DE) | 1986-04-02 | — | — | EP | disclosed |
| US-4560751-A | CYCLIZATION OF AMIDO-THIOAMIDE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| EP-0100018-A1 | Process for the production of 2-N,N-disubstituted aminothiazoles | BASF Aktiengesellschaft (DE) | 1984-02-08 | — | — | EP | disclosed |
| US-4167394-A | MONOAZO DYES HAVING INDOLE OR PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1979-09-11 | — | — | US | disclosed |
| US-4154577-A | Uniformly disperse dyed water-swellable cellulosic fibers | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-15 | — | — | US | disclosed |
| US-4083686-A | AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |