SCHEMBL83489

SCHEMBL83489

CCCCc1ccc(CCCC)c(N)c1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.61
TLR8 Q9NR97 7/20 0.44
TYR P14679 1/20 0.44
CA2 P00918 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTR1A P08908 1/20 0.43
HTR2A P28223 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL84181 0.98 SKP2 (0.59) SKP2TLR8TYRCA2SMN1; SMN2
SCHEMBL5830877 0.85 HTR2A (0.53) SKP2TLR8CA2HTR2A
SCHEMBL2958383 0.85 SKP2 (0.53) SKP2TLR8CA2HTR1AHTR2A
SCHEMBL8375841 0.84 SKP2 (0.67) SKP2TLR8CA2SMN1; SMN2HTR1A
SCHEMBL27705882 0.84 SKP2 (0.45) SKP2TLR8TYRHPGD
SCHEMBL7204931 0.83 SKP2 (0.71) SKP2CA2SMN1; SMN2HTR1AHTR2A
SCHEMBL29511379 0.83 SKP2 (0.71) SKP2CA2SMN1; SMN2HTR1AHTR2A
SCHEMBL8781871 0.83 SKP2 (0.46) SKP2CA2SMN1; SMN2NPC1RAB9A
SCHEMBL5830312 0.83 HTR2A (0.47) SKP2TLR8TYRSMN1; SMN2HTR2A
SCHEMBL10492538 0.82 TYR (0.46) SKP2TLR8TYRHTR2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
EP-2139977-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-06 EP claimed
WO-2008123940-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-16 WO claimed
US-7211202-B2 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ATOFINA (FR) 2007-05-01 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
US-6764617-B1 AND FERROMAGNETIC IRON OXIDE PARTICLES; ELECTROMAGNETIC SHIELDS; ACID RESISTANCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS & SPACE ADMINISTRATION 2004-07-20 US claimed
US-5968417-A Conducting compositions of matter THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1999-10-19 US claimed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants SAS Nanotechnologies Inc. (US) 2023-02-14 US disclosed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP disclosed
EP-3823745-A1 STIMULI-RESPONSIVE MICRO-RESERVOIRS FOR RELEASE OF ENCAPSULANTS SAS Nanotechnologies LLC (US) 2021-05-26 EP disclosed
WO-2020018555-A1 STIMULI-RESPONSIVE MICRO-RESERVOIRS FOR RELEASE OF ENCAPSULANTS SAS Nanotechnologies LLC (US) 2020-01-23 WO disclosed
US-20120142781-A1 Antagonists of the Magnesium Binding Defect as Therapeutic Agents and Methods for Treatment of Abnormal Physiological States MAGNESIUM DIAGNOSTICS INC. (US) 2012-06-07 US disclosed
US-20120142781-A1 Antagonists of the Magnesium Binding Defect as Therapeutic Agents and Methods for Treatment of Abnormal Physiological States MAGNESIUM DIAGNOSTICS INC. (US) 2012-06-07 US disclosed
US-5456862-A Thermally stable forms of electrically conductive polyaniline ALLIEDSIGNAL INC. (US) 1995-10-10 US disclosed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US disclosed
EP-0589529-A1 Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1994-03-30 EP disclosed
US-5278213-A Low viscosity solution ALLIED SIGNAL INC. (US) 1994-01-11 US disclosed
US-5262483-A Styrene-maleic anhydride and polyaniline grafted with processability and conductivity DSM N.V. (NL) 1993-11-16 US disclosed
EP-0538939-A1 Polymer composition DSM N.V. (NL) 1993-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142781-A1 Antagonists of the Magnesium Binding Defect as Therapeutic Agents and Methods for Treatment of Abnormal Physiological States PLPBP, ECE1, MCU SKP2 4478/4885TLR8 4784/4885TYR 4844/4885
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants ORAI1, CD44, VAPA SKP2 3285/4885TLR8 1963/4885TYR 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.