Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.32 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962761 | 0.90 | PANK3 (0.35) | PANK3CTSKCTSCRORC | |
| SCHEMBL8963181 | 0.87 | FFAR4 (0.31) | — | |
| SCHEMBL8963174 | 0.87 | FFAR4 (0.31) | — | |
| SCHEMBL12975806 | 0.84 | SPHK1 (0.32) | PANK3CTSKCTSCRORC | |
| SCHEMBL9300544 | 0.84 | — | — | |
| SCHEMBL8962654 | 0.82 | KDM1A (0.34) | — | |
| SCHEMBL8963109 | 0.81 | SLC6A3 (0.33) | — | |
| SCHEMBL12975943 | 0.80 | — | — | |
| SCHEMBL12975949 | 0.80 | — | — | |
| SCHEMBL10409027 | 0.80 | CYP2C9 (0.44) | PANK3CTSKCTSCRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |