Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963174 | 1.00 | FFAR4 (0.31) | FFAR4NR1H4SPHK1 | |
| SCHEMBL8962629 | 0.90 | HDAC2 (0.33) | FFAR4NR1H4 | |
| SCHEMBL8962633 | 0.90 | HDAC2 (0.33) | FFAR4NR1H4 | |
| SCHEMBL8963313 | 0.87 | PANK3 (0.32) | — | |
| SCHEMBL9540776 | 0.85 | SLC6A3 (0.36) | — | |
| SCHEMBL8962781 | 0.85 | NAAA (0.34) | FFAR4NR1H4 | |
| SCHEMBL8962789 | 0.85 | NAAA (0.34) | FFAR4NR1H4 | |
| SCHEMBL8963237 | 0.82 | P2RY14 (0.35) | — | |
| SCHEMBL8963228 | 0.82 | P2RY14 (0.35) | — | |
| SCHEMBL8962838 | 0.81 | SLC6A3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |