Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963355 | 0.74 | MAPT (0.44) | ALDH1A1POLBLMNAL3MBTL1TSHR | |
| SCHEMBL9462849 | 0.69 | TSHR (0.49) | ALDH1A1POLBTSHRMAPTNPC1 | |
| SCHEMBL9754199 | 0.69 | ALDH1A1 (0.53) | GAAALDH1A1POLBTSHRMAPT | |
| SCHEMBL18415560 | 0.66 | MAPT (0.51) | ALDH1A1POLBTSHRMAPTMEN1 | |
| SCHEMBL1731363 | 0.66 | GAA (0.53) | GAAALDH1A1POLBHTTLMNA | |
| SCHEMBL10683818 | 0.66 | MAPT (0.59) | GAAL3MBTL1TSHRMAPT | |
| SCHEMBL7959792 | 0.65 | MAPT (0.50) | GAAALDH1A1LMNATSHRMAPT | |
| SCHEMBL6816672 | 0.64 | NPC1 (0.49) | GAAALDH1A1HTTTSHRMAPT | |
| SCHEMBL7959789 | 0.64 | CYP3A4 (0.49) | ALDH1A1POLBTSHRMAPTKMT2A | |
| SCHEMBL9641181 | 0.64 | CYP3A4 (0.49) | ALDH1A1TSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | claimed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |