Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 16/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963868 | 0.82 | DRD2 (0.63) | DRD2DRD4DRD3CTSSLMNA | |
| Hydrochloric Acid SCHEMBL8963575 | 0.78 | DRD4 (0.35) | DRD2DRD4DRD3TSHR | |
| Hydrochloric Acid SCHEMBL8963519 | 0.77 | HTR1A (0.36) | DRD2DRD4DRD3TSHR | |
| Hydrochloric Acid SCHEMBL8963955 | 0.77 | MAPK14 (0.35) | DRD2DRD4DRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8964019 | 0.76 | DRD2 (0.71) | DRD2DRD4DRD3CTSSLMNA | |
| Hydrochloric Acid SCHEMBL8963901 | 0.76 | DRD2 (0.34) | DRD2DRD4DRD3LMNAALDH1A1 | |
| SCHEMBL9720664 | 0.76 | DRD2 (0.62) | DRD2DRD4DRD3CTSS | |
| SCHEMBL9424741 | 0.75 | DRD3 (0.55) | DRD2DRD4DRD3CTSSLMNA | |
| SCHEMBL9720670 | 0.75 | DRD4 (0.57) | DRD2DRD4DRD3CTSSLMNA | |
| Hydrochloric Acid SCHEMBL8963570 | 0.75 | DRD2 (0.33) | DRD2DRD4DRD3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |