Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8964115 | 0.74 | DRD2 (0.37) | NPY5RMAPTPRMT5 | |
| Hydrochloric Acid SCHEMBL8963582 | 0.73 | CETP (0.33) | PRCPCETPCXCR2NPY5RLMNA | |
| Hydrochloric Acid SCHEMBL8963768 | 0.73 | NPY5R (0.38) | PRCPCETPNPY5RPRMT5SLC2A1 | |
| Hydrochloric Acid SCHEMBL8963523 | 0.72 | CETP (0.32) | CETPPRMT5SLC2A1 | |
| Hydrochloric Acid SCHEMBL8963834 | 0.72 | DRD2 (0.35) | NPY5RPRMT5 | |
| Hydrochloric Acid SCHEMBL8963446 | 0.71 | PRMT5 (0.36) | CETPNPY5RALDH1A1TSHRPRMT5 | |
| SCHEMBL8963897 | 0.71 | PRMT5 (0.36) | NPY5RALDH1A1PRMT5KMT2AHTR3A | |
| Hydrochloric Acid SCHEMBL8963569 | 0.71 | NPY5R (0.38) | CETPNPY5RLMNAKMT2ASLC2A1 | |
| SCHEMBL8963837 | 0.70 | PRMT5 (0.35) | NPY5RALDH1A1LMNAMAPTDGAT1 | |
| Hydrochloric Acid SCHEMBL8963626 | 0.69 | CETP (0.36) | CETPNPY5RLMNAMAPTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |