Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8963752 | 0.94 | DRD2 (0.35) | PRMT5KHKSLC6A4DRD2DRD4 | |
| SCHEMBL8963837 | 0.93 | PRMT5 (0.35) | PRMT5TNKSPARP1TNKS2KHK | |
| SCHEMBL8963987 | 0.90 | PRMT5 (0.35) | PRMT5TNKSPARP1TNKS2KHK | |
| Hydrochloric Acid SCHEMBL8963445 | 0.89 | PRMT5 (0.34) | PRMT5TNKSPARP1TNKS2KHK | |
| Hydrochloric Acid SCHEMBL8963841 | 0.87 | DRD2 (0.35) | PRMT5KHKSLC6A4DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8964022 | 0.79 | NPY5R (0.37) | PRMT5TNKSPARP1TNKS2HTR3A | |
| SCHEMBL8963765 | 0.79 | OPRD1 (0.35) | PRMT5TNKSPARP1TNKS2KHK | |
| SCHEMBL8963935 | 0.78 | NPY5R (0.40) | PRMT5SLC6A4DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8963692 | 0.78 | PRMT5 (0.36) | PRMT5SLC6A4DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8963711 | 0.78 | PRMT5 (0.34) | PRMT5TNKSPARP1TNKS2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |