SCHEMBL896379

SCHEMBL896379

c1ccc(CN2CCOCCOCCN(Cc3ccccc3)CCOCCOCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.68
HRH3 Q9Y5N1 2/20 0.68
ALDH1A1 P00352 4/20 0.63
HTT P42858 2/20 0.63
KDM4E B2RXH2 1/20 0.63
HPGD P15428 1/20 0.63
NCF1 P14598 1/20 0.61
DRD4 P21917 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
TSHR P16473 1/20 0.59
CYP2A13 Q16696 2/20 0.59
POLB P06746 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
KCNJ1 P48048 1/20 0.57
MC4R P32245 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948372 1.00 SIGMAR1 (0.68) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL18065638 1.00 SIGMAR1 (0.68) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL102338 0.98 SIGMAR1 (0.71) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL6200777 0.98 SIGMAR1 (0.71) SIGMAR1HRH3ALDH1A1HTTKDM4E
Water SCHEMBL1702298 0.96 SIGMAR1 (0.68) SIGMAR1HRH3ALDH1A1HTTKDM4E
Hydrochloric Acid SCHEMBL6261135 0.96 SIGMAR1 (0.68) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL28158277 0.96 SIGMAR1 (0.68) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL6384833 0.94 HRH3 (0.61) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL18309364 0.94 HRH3 (0.61) SIGMAR1HRH3ALDH1A1HTTKDM4E
SCHEMBL24200050 0.93 HRH3 (0.62) SIGMAR1HRH3ALDH1A1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110873-A1 SENSOR FOR DETECTING TRACE IONS AND METHOD THEREOF VULCAN PHOTONICS SDN. BHD. (MY) 2025-05-30 WO claimed
US-20250093308-A1 MILLIFLUIDIC CHROMATOGRAPHY PLATE VULCAN PHOTONICS SDN. BHD. (MY) 2025-03-20 US claimed
US-20250082793-A1 MACROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME JANSSEN BIOTECH, INC. 2025-03-13 US claimed
CN-119234151-A Millifluidic chromatography plate 伏尔甘光电私人有限公司 2024-12-31 CN claimed
EP-4476542-A1 MILLIFLUIDIC CHROMATOGRAPHY PLATE Vulcan Photonics SDN. BHD. (MY) 2024-12-18 EP claimed
WO-2024248601-A1 METHOD FOR PREPARING MODIFIED LIGANDS FOR DETECTING IONS VULCAN PHOTONICS SDN. BHD. (MY) 2024-12-05 WO claimed
WO-2024225888-A1 MILLIFLUIDIC CHROMATOGRAPHY PLATE VULCAN PHOTONICS SDN. BHD. (MY) 2024-10-31 WO claimed
EP-4430040-A1 MACROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME Janssen Biotech, Inc. (US) 2024-09-18 EP claimed
CN-118515556-A Preparation method of caprylic-capric glyceride 万华化学集团股份有限公司 2024-08-20 CN claimed
CN-118201925-A Macrocyclic compounds and methods of making the same 詹森生物科技公司 2024-06-14 CN claimed
EP-1858990-A1 INK COMPOSITION FOR CONTINUOUS DEFLECTED INK JET PRINTING IMAJE S.A. (FR) 2007-11-28 EP claimed
WO-2006097502-A1 INK COMPOSITION FOR CONTINUOUS DEFLECTED INK JET PRINTING IMAJE S.A. (FR) 2006-09-21 WO claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5702804-A Recording sheets XEROX CORPORATION (US) 1997-12-30 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082793-A1 MACROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME PAICS, CD47, FURIN SIGMAR1 4561/4885HRH3 2500/4885ALDH1A1 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.