Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067630 | 0.89 | TAAR1 (0.35) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL7558089 | 0.79 | TAAR1 (0.34) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL7557369 | 0.73 | TAAR1 (0.35) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL6161969 | 0.73 | TAAR1 (0.58) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL7519877 | 0.72 | TAAR1 (0.36) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL25579654 | 0.68 | TAAR1 (0.44) | TAAR1FNTAFNTB | |
| SCHEMBL8239748 | 0.67 | TAAR1 (0.50) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL8067779 | 0.67 | TAAR1 (0.42) | TAAR1FNTAFNTBDRD1DRD2 | |
| SCHEMBL1798685 | 0.66 | CYP1A2 (0.53) | TAAR1 | |
| SCHEMBL6669711 | 0.66 | TAAR1 (0.40) | TAAR1FNTAFNTBUSP2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695293-A1 | 10,11-METHANODIBENZOSUBERANE DERIVATIVES USED AS CHEMOSENSITIZING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024107-A1 | 10,11-METHANODIBENZOSUBERANE DERIVATIVES USED AS CHEMOSENSITIZING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1994-10-27 | — | — | WO | disclosed |