Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 17/20 | 0.46 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963744 | 0.75 | DRD2 (0.71) | DRD2DRD4DRD3CTSS | |
| SCHEMBL8964019 | 0.75 | DRD2 (0.71) | DRD2DRD4DRD3CTSS | |
| SCHEMBL8964201 | 0.74 | DRD3 (0.55) | DRD2DRD4DRD3CTSS | |
| SCHEMBL8834289 | 0.70 | DRD4 (1.00) | DRD2DRD4DRD3CTSS | |
| SCHEMBL8963668 | 0.70 | DRD2 (0.64) | DRD2DRD4DRD3CTSS | |
| SCHEMBL8964204 | 0.70 | SLC6A2 (0.34) | DRD2DRD4DRD3 | |
| SCHEMBL8963868 | 0.69 | DRD2 (0.63) | DRD2DRD4DRD3CTSS | |
| SCHEMBL9720664 | 0.69 | DRD2 (0.62) | DRD2DRD4DRD3CTSSGNRHR | |
| SCHEMBL8963465 | 0.69 | LMNA (0.57) | DRD2DRD4DRD3CTSSGNRHR | |
| SCHEMBL8963624 | 0.68 | DRD2 (0.47) | DRD2DRD4DRD3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |