Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667761 | 0.72 | MAOA (0.45) | MAOAMAOBGAAKDM4EALDH1A1 | |
| SCHEMBL29438383 | 0.72 | MAOA (0.45) | MAOAMAOBGAAKDM4EALDH1A1 | |
| SCHEMBL8657090 | 0.69 | MAOA (0.36) | MAOAMAOBALDH1A1CASP7L3MBTL1 | |
| SCHEMBL9087669 | 0.69 | KDM4E (0.42) | MAOAMAOBGAAKDM4EALDH1A1 | |
| SCHEMBL11391339 | 0.67 | MAOA (0.48) | MAOAMAOBGAANPC1LMNA | |
| SCHEMBL276959 | 0.67 | MAOA (0.48) | MAOAMAOBGAANPC1LMNA | |
| SCHEMBL10869264 | 0.67 | MAOB (0.43) | MAOAMAOBGAANPC1LMNA | |
| SCHEMBL311687 | 0.67 | MAOB (0.39) | MAOAMAOBGAALMNARAB9A | |
| SCHEMBL7868192 | 0.67 | MAOA (0.39) | MAOAMAOBGAANPSR1 | |
| SCHEMBL6622506 | 0.66 | PTGS2 (0.47) | KDM4EALDH1A1HPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482942-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS AND MUSCULAR DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-09 | — | — | US | disclosed |