Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930667 | 0.91 | L3MBTL3 (0.49) | HSD17B14L3MBTL3L3MBTL1L3MBTL4PRKCQ | |
| SCHEMBL8964576 | 0.89 | L3MBTL3 (0.57) | HSD17B14L3MBTL3L3MBTL1L3MBTL4PRKCQ | |
| SCHEMBL8964827 | 0.88 | L3MBTL3 (0.56) | HSD17B14L3MBTL3L3MBTL1L3MBTL4HRH3 | |
| SCHEMBL8963966 | 0.86 | HSD17B14 (0.55) | HSD17B14PRKCQHTTALOX15ALDH1A1 | |
| SCHEMBL9010620 | 0.82 | PRKCQ (0.54) | HSD17B14PRKCQ | |
| SCHEMBL8964283 | 0.80 | HSD17B14 (0.45) | HSD17B14L3MBTL3L3MBTL1HTTALOX15 | |
| SCHEMBL8964520 | 0.78 | HTT (0.49) | HSD17B14L3MBTL3L3MBTL1PRKCQHRH3 | |
| SCHEMBL8964433 | 0.77 | HSD17B14 (0.44) | HSD17B14PRKCQHRH3HTTALOX15 | |
| SCHEMBL8964454 | 0.77 | HSD17B14 (0.42) | HSD17B14PRKCQHTTALOX15ALDH1A1 | |
| SCHEMBL8964288 | 0.77 | PIM1 (0.45) | HSD17B14L3MBTL3L3MBTL1PRKCQHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-07 | — | — | US | disclosed |
| US-8188071-B2 | Amino substituted pyridines as potent kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K6 | HSD17B14 2544/4885L3MBTL3 2612/4885L3MBTL1 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.