Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964583 | 0.77 | NPY5R (0.51) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL8964550 | 0.77 | RPS6KA3 (0.46) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL8964784 | 0.76 | MAPT (0.46) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL25027819 | 0.72 | KDM1A (0.48) | NPC1HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL27837417 | 0.71 | NPY5R (0.52) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL29643308 | 0.70 | MAPT (0.67) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL156150 | 0.70 | MAPT (0.67) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9119652 | 0.70 | MAPT (0.57) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2790890 | 0.69 | MAPT (0.69) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL27769428 | 0.68 | MAPT (0.68) | NPC1RAB9AHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |