Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15251711 | 0.76 | CA2 (0.37) | KMT2A | |
| SCHEMBL5455128 | 0.74 | CA2 (0.56) | KMT2A | |
| SCHEMBL10804149 | 0.72 | CA2 (0.34) | KMT2A | |
| SCHEMBL17394566 | 0.72 | TSHR (0.43) | — | |
| SCHEMBL8964346 | 0.72 | CA2 (0.52) | KMT2A | |
| SCHEMBL8964679 | 0.71 | CDK1 (0.39) | KMT2A | |
| SCHEMBL8858040 | 0.70 | MEN1 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL8964637 | 0.70 | IDO1 (0.50) | — | |
| SCHEMBL20618816 | 0.70 | IDO1 (0.44) | KMT2ASMN1; SMN2 | |
| SCHEMBL8964685 | 0.70 | IDO1 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410379-B1 | Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins | MERRELL DOW PHARMA (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5068465-A | Hypotensive agents or enzyme inhibitors for treatment of hypertension | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0410379-A2 | Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-30 | — | — | EP | disclosed |
| US-4981868-A | ENZYME INHIBITORS, HYPOTENSIVES | MERRELL DOW PHARMACEUTICAL (US) | 1991-01-01 | — | — | US | disclosed |