Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 6/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL18130856 | 1.00 | PTGER2 (0.44) | PTGER2PTGER3PTGER4HTTTLR4 | |
| Acetic Acid SCHEMBL1482741 | 1.00 | PTGER2 (0.44) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL158776 | 0.92 | CYP1A2 (0.43) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL8964738 | 0.92 | CYP1A2 (0.43) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL8965184 | 0.92 | CYP1A2 (0.43) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL8964734 | 0.92 | CYP1A2 (0.43) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL8965187 | 0.92 | CYP1A2 (0.43) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL8600712 | 0.90 | CYP1A2 (0.46) | PTGER2PTGER3PTGER4HTTTSHR | |
| Acetic Acid Methyl Ester SCHEMBL28101633 | 0.89 | HTT (0.45) | PTGER2PTGER3PTGER4HTTTLR4 | |
| SCHEMBL1614409 | 0.86 | HTT (0.40) | PTGER2PTGER3PTGER4HTTTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209281-A1 | 2,4-DIMETHYLOCTA-2,7-DIEN-4-OL AS AN ODORIFEROUS SUBSTANCE | SYMRISE AG (DE) | 2024-06-27 | — | — | US | claimed |
| US-20240141254-A1 | 2,6,6-TRIMETHYL-NORPINAN-2-OL AS AN ODORIFEROUS SUBSTANCE | SYMRISE AG (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4330361-A1 | 2,4-DIMETHYLOCTA-2,7-DIEN-4-OL AS AN ODORIFEROUS SUBSTANCE | Symrise AG (DE) | 2024-03-06 | — | — | EP | claimed |
| EP-4305135-A1 | 2,6,6-TRIMETHYL-NORPINAN-2-OL AS AN ODORIFEROUS SUBSTANCE | Symrise AG (DE) | 2024-01-17 | — | — | EP | claimed |
| CN-117203313-A | 2, 4-dimethyloctan-2, 7-dien-4-ol as perfume | 西姆莱斯股份公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116964182-A | 2, 6-trimethyl-pinan-2-ol as fragrance | 西姆莱斯股份公司 | 2023-10-27 | — | — | CN | claimed |
| WO-2022228658-A1 | 2,4-DIMETHYLOCTA-2,7-DIEN-4-OL AS AN ODORIFEROUS SUBSTANCE | SYMRISE AG (DE) | 2022-11-03 | — | — | WO | claimed |
| EP-0394810-B1 | PROCESS OF SCENTING | FIRMENICH SA (CH) | 1993-10-13 | — | — | EP | claimed |
| US-5116656-A | Mixture with another ingredient to enhance efficiency of transfer | FIRMENICH SA (CH) | 1992-05-26 | — | — | US | claimed |
| US-12529008-B2 | Natural semi-solid perfume | EXPRESSIONS PARFUMEES (FR) | 2026-01-20 | — | — | US | disclosed |
| US-12290583-B2 | Perfuming complex, perfuming composition and perfumed aqueous composition of natural origin | EXPRESSIONS PARFUMÉES (FR) | 2025-05-06 | — | — | US | disclosed |
| EP-4489721-A1 | READY-FOR-USE MILKY, VISCOUS AND STICKY PERFUME COMPLEX AND ASSOCIATED PERFUMED COMPOSITION | Expressions Parfumees (FR) | 2025-01-15 | — | — | EP | disclosed |
| US-20240415745-A1 | PERFUMING COMPLEX, PERFUMING COMPOSITION AND PERFUMED AQUEOUS COMPOSITION OF NATURAL ORIGIN | EXPRESSIONS PARFUMÉES (FR) | 2024-12-19 | — | — | US | disclosed |
| EP-4419065-A1 | FRAGRANCING COMPLEX, FRAGRANCING COMPOSITION AND FRAGRANCED AQUEOUS COMPOSITION OF NATURAL ORIGIN | Expressions Parfumees (FR) | 2024-08-28 | — | — | EP | disclosed |
| US-20180112152-A1 | PROCESS FOR PREPARING POLYUREA MICROCAPSULES | FIRMENICH SA (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180078468-A1 | MICROCAPSULES WITH HIGH DEPOSITION ON SURFACES | FIRMENICH SA (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20090081755-A1 | FRAGRANT CONSUMER PRODUCTS COMPRISING OXIDIZING AGENTS | HENKEL AG & CO. KG A (DE) | 2009-03-26 | — | — | US | disclosed |
| US-6479456-B1 | PERFUMED PRODUCTS (SUCH AS BODY CARE PRODUCTS, DETERGENTS ETC.) NOT ONLY GIVES OFF PLEASANT ODOR, BUT INCREASES, SYNERGISTICALLY, THE ANTIMICROBIAL ACTVITY; GRAPEFRUIT-PIT EXTRACT, FUMITORY EXTRACT, FUMARIC ACID, OR IT'S ESTER | FIRMENICH SA (CH) | 2002-11-12 | — | — | US | disclosed |
| US-5116656-A | Mixture with another ingredient to enhance efficiency of transfer | FIRMENICH SA (CH) | 1992-05-26 | — | — | US | disclosed |
| EP-0394810-A1 | Process of scenting | FIRMENICH SA (CH) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12290583-B2 | Perfuming complex, perfuming composition and perfumed aqueous composition of natural origin | DAGLA, DAGLB, CAPRIN1 | PTGER2 1073/4885PTGER3 1278/4885PTGER4 2072/4885 |
| US-20240415745-A1 | PERFUMING COMPLEX, PERFUMING COMPOSITION AND PERFUMED AQUEOUS COMPOSITION OF NATURAL ORIGIN | DAGLA, DAGLB, CAPRIN1 | PTGER2 1073/4885PTGER3 1278/4885PTGER4 2072/4885 |
| US-12529008-B2 | Natural semi-solid perfume | TES, TAS2R50, TAS2R10 | PTGER2 195/4885PTGER3 500/4885PTGER4 647/4885 |
| US-20240141254-A1 | 2,6,6-TRIMETHYL-NORPINAN-2-OL AS AN ODORIFEROUS SUBSTANCE | OR10J3, OR51E2, SRD5A2 | PTGER2 320/4885PTGER3 1369/4885PTGER4 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.