Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754531 | 0.85 | AHR (0.47) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21295695 | 0.78 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL5367660 | 0.78 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21295786 | 0.75 | MAPT (0.44) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2089391 | 0.74 | MEN1 (0.44) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16919496 | 0.73 | AHR (0.71) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL571563 | 0.73 | AHR (0.71) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL905380 | 0.72 | MAOA (0.72) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL3874960 | 0.72 | AHR (0.59) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| Dibenzofuran SCHEMBL8207 | 0.72 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |