Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964550 | 0.88 | RPS6KA3 (0.46) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL8964877 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL12408905 | 0.71 | NPC1 (0.84) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL8964782 | 0.70 | NPC1 (0.41) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL11551873 | 0.69 | NPC1 (0.81) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL8964790 | 0.69 | RPS6KA3 (0.53) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL27817965 | 0.69 | NPY5R (0.52) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30959742 | 0.68 | NPC1 (0.64) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL802768 | 0.68 | HSD17B10 (0.60) | NPC1RAB9ARPS6KA3SMN1; SMN2KDM4E | |
| SCHEMBL12963754 | 0.68 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |