Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964550 | 0.81 | RPS6KA3 (0.46) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8964836 | 0.79 | CNR2 (0.31) | KDM4EESR1ESR2 | |
| SCHEMBL8964877 | 0.71 | ALDH1A1 (0.43) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8964781 | 0.70 | NPC1 (0.52) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8964790 | 0.67 | RPS6KA3 (0.53) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL12304267 | 0.66 | HSD17B10 (0.66) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL802768 | 0.65 | HSD17B10 (0.60) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8964793 | 0.65 | RPS6KA3 (0.54) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL27817965 | 0.64 | NPY5R (0.52) | NPC1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8964898 | 0.63 | RPS6KA3 (0.49) | NPC1RAB9AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |