Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP12 | P39900 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486355 | 0.83 | TDP1 (0.51) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL8881808 | 0.82 | MAPT (0.58) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL9186731 | 0.82 | PDE7A (0.56) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL2960260 | 0.82 | PDE7A (0.62) | SMN1; SMN2PDE7AKMT2ANPC1RAB9A | |
| SCHEMBL1713219 | 0.81 | PDE7A (0.65) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL30338244 | 0.81 | PDE7A (0.65) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL12953529 | 0.81 | PDE7A (0.48) | SMN1; SMN2PDE7AKMT2ATDP1ALDH1A1 | |
| SCHEMBL810656 | 0.81 | TDP1 (0.58) | PDE7AKMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL811285 | 0.80 | PDE7A (0.60) | PDE7AKMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL30548759 | 0.79 | MEN1 (0.62) | KMT2AALDH1A1MEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |
| US-4124370-A | Diphenyl ethers for tobacco sucker control | ROHM AND HAAS COMPANY (US) | 1978-11-07 | — | — | US | disclosed |