Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186731 | 0.86 | PDE7A (0.56) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL30338244 | 0.85 | PDE7A (0.65) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL1713219 | 0.85 | PDE7A (0.65) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL1341344 | 0.85 | PDE7A (0.54) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL7665295 | 0.83 | PDE7A (0.67) | PDE7ASMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL10923003 | 0.83 | PDE7A (0.65) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL2614719 | 0.83 | PDE7A (0.59) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL2959825 | 0.83 | MAPT (0.71) | MAPTALDH1A1PDE7AMEN1KMT2A | |
| SCHEMBL11760310 | 0.83 | PDE7A (0.56) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 | |
| SCHEMBL2414180 | 0.82 | PDE7A (0.51) | MAPTALDH1A1PDE7ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113813-A1 | MECHANOCHEMICAL SNAR REACTIONS | UNIVERSITY OF CINCINNATI (US) | 2021-06-10 | — | — | WO | disclosed |
| US-7867980-B2 | Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 2010-07-22 | — | — | US | disclosed |
| US-5679695-A | Aryl and heteroaryl compounds having anti-retrovirus activity | THE UNIVERSITY OF CONNECTICUT (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0554377-A4 | ARYL AND HETEROARYL COMPOUNDS HAVING ANTI-RETROVIRUS ACTIVITY | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0554377-A1 | ARYL AND HETEROARYL COMPOUNDS HAVING ANTI-RETROVIRUS ACTIVITY | THE UNIVERSITY OF CONNECTICUT (US) | 1993-08-11 | — | — | EP | disclosed |
| WO-1992006683-A1 | ARYL AND HETEROARYL COMPOUNDS HAVING ANTI-RETROVIRUS ACTIVITY | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-04-30 | — | — | WO | disclosed |
| US-4912112-A | Substituted 2,4-diamino-5-benzylpyrimidines, their preparation and their use as medicaments with an antimicrobial activity | SAARSTICKSTOFF-FATOL GMBH CHEM.-PHARM. FABRIK (DE) | 1990-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | SIRT6, LAS1L, MRPS18A | MAPT 2807/4885ALDH1A1 3217/4885PDE7A 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.