Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 6/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | MMP12 | P39900 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548759 | 0.86 | MEN1 (0.62) | MEN1KMT2APOLBDHFRMMP2 | |
| SCHEMBL25385867 | 0.81 | DHFR (0.57) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL30567150 | 0.81 | DHFR (0.57) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL14486804 | 0.80 | PTGIR (0.49) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL2887154 | 0.79 | AR (0.55) | MEN1KMT2APOLBDHFRMMP2 | |
| SCHEMBL20591216 | 0.79 | MEN1 (0.55) | MEN1KMT2APOLBDHFRMMP2 | |
| SCHEMBL2970197 | 0.79 | SLC6A2 (0.57) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL546833 | 0.79 | DHFR (0.49) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL3095695 | 0.78 | CYP3A4 (0.56) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL3542179 | 0.78 | MEN1 (0.54) | MEN1KMT2APOLBDHFRMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |