Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964787 | 0.89 | MAPT (0.52) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8964809 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL8964567 | 0.86 | HDAC6 (0.47) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL8964811 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL8964793 | 0.81 | RPS6KA3 (0.54) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8965246 | 0.72 | NPC1 (0.55) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL24090336 | 0.71 | AHR (0.47) | NPC1RAB9AAHR | |
| SCHEMBL24552409 | 0.71 | AHR (0.55) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL29298687 | 0.70 | KDM4E (0.52) | KDM4EALDH1A1NPC1RAB9ACASP3 | |
| SCHEMBL13522796 | 0.69 | KDM6B (0.73) | KDM4EALDH1A1NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |