Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM6A | O15550 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964805 | 0.89 | KDM4E (0.52) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL8964793 | 0.88 | RPS6KA3 (0.54) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL8964809 | 0.88 | KDM4E (0.49) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL8964567 | 0.87 | HDAC6 (0.47) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL9292938 | 0.79 | KDM6B (0.55) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL8964800 | 0.76 | KDM6B (0.64) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL1296601 | 0.73 | KDM6B (0.78) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL30096340 | 0.73 | ALDH1A1 (0.65) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL29627559 | 0.73 | ALDH1A1 (0.65) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL30682 | 0.73 | ALDH1A1 (0.65) | MAPTKDM4EALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |