Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CYP21A2 | P08686 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978296 | 0.90 | MAPT (0.40) | PGRCYP17A1CYP21A2CYP11B1MAPT | |
| SCHEMBL15805936 | 0.87 | CHRNB4 (0.50) | PGRCHRNB4CHRNA3CYP17A1CYP21A2 | |
| SCHEMBL10042442 | 0.86 | ALDH1A1 (0.52) | PGRCHRNB4CHRNA3CYP17A1CYP21A2 | |
| SCHEMBL7503144 | 0.84 | ALDH1A1 (0.48) | PGRCHRNB4CHRNA3CYP17A1CYP21A2 | |
| SCHEMBL19665086 | 0.82 | BCL2L1 (0.44) | PGRCYP17A1CYP21A2CYP11B1MAPT | |
| SCHEMBL505073 | 0.80 | CYP17A1 (0.60) | CHRNB4CHRNA3CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL1987073 | 0.80 | CYP17A1 (0.50) | PGRCYP17A1CYP21A2CYP11B1MAPT | |
| SCHEMBL3605667 | 0.77 | AGXT (0.39) | CYP17A1CYP21A2CYP11B1MAPTBCL2L1 | |
| SCHEMBL12562840 | 0.76 | MAPK1 (0.55) | MAPTBCL2L1BADGABRPGABRD | |
| SCHEMBL787631 | 0.76 | MAPK1 (0.55) | MAPTBCL2L1BADGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |