Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562840 | 1.00 | MAPK1 (0.55) | MAPK1ALDH1A1CYP2A6LMNAMEN1 | |
| SCHEMBL9457196 | 1.00 | MAPK1 (0.55) | MAPK1ALDH1A1CYP2A6LMNAMEN1 | |
| SCHEMBL1991704 | 1.00 | MAPK1 (0.55) | MAPK1ALDH1A1CYP2A6LMNAMEN1 | |
| SCHEMBL8863391 | 0.97 | MAPK1 (0.52) | MAPK1ALDH1A1CYP2A6LMNAMEN1 | |
| SCHEMBL1622 | 0.90 | — | — | |
| SCHEMBL7026005 | 0.90 | — | — | |
| Fluoride SCHEMBL25376004 | 0.87 | CYP2A6 (0.57) | MAPK1ALDH1A1CYP2A6LMNAMEN1 | |
| SCHEMBL164941 | 0.87 | — | — | |
| SCHEMBL4600807 | 0.87 | — | — | |
| SCHEMBL197346 | 0.83 | BCL2L1 (0.55) | MAPTSMN1; SMN2BCL2L1BADCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57040429-A | — | — | None | — | — | JP | disclosed |
| JP-56169633-A | — | — | None | — | — | JP | disclosed |
| WO-2026090589-A1 | HETEROCYCLIC HBS1L DEGRADERS | TANGO THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| CN-120058445-A | Method for generating aryl phenol compound by hydroxylation of uranium photocatalytic aryl fluorine compound and application of method | 华东师范大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-118994001-A | NOTCH signaling pathway inhibitors and their use in cancer treatment | 塞莱斯蒂亚生物技术股份公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113966324-B | NOTCH signaling pathway inhibitors and their use in cancer treatment | 塞莱斯蒂亚生物技术股份公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2024167142-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 랩토 | 2024-08-15 | — | — | WO | disclosed |
| CN-109096217-B | Heterocyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
| US-20230399287-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
| US-4723033-A | REACTING ALPHA METAL ACID DERIVATIVE AND ARYL HALIDE WITH OPTICALLY ACTIVE CATALYST | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1988-02-02 | — | — | US | disclosed |
| EP-0110671-B1 | PREPARATION OF OPTICALLY ACTIVE ALPHA-ARYLALKANOIC ACIDS AND PRECURSORS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-05-21 | — | — | EP | disclosed |
| EP-0110671-A1 | Preparation of optically active alpha-arylalkanoic acids and precursors thereof | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1984-06-13 | — | — | EP | disclosed |
| JP-S5740429-A | 4-(4-N-ALKYL-1-CYCLOHEXEN-1-YL)-4'-FLUOROBIPHENYL | CHISSO CORP | 1982-03-06 | — | — | JP | disclosed |
| JP-S56169633-A | 4-(4-TRANS-N-ALKYLCYCLOHEXYL)-4'-FLUOROBIPHENYL | CHISSO CORP | 1981-12-26 | — | — | JP | disclosed |
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |
| US-4060633-A | Phenylalkanol nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-29 | — | — | US | disclosed |
| US-3980795-A | Pyrazolidinones and a process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399287-A1 | NOVEL COMPOUNDS | CNKSR1, RORC, HLA-DRB1 | MAPK1 731/4885ALDH1A1 182/4885CYP2A6 748/4885 |
| US-20230399289-A1 | ITACONIC ACID DERIVATIVES | IL1R1, LRBA, HCAR1 | MAPK1 860/4885ALDH1A1 28/4885CYP2A6 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.