SCHEMBL8965038

SCHEMBL8965038

C=Cc1ccc(C(=O)C=Cc2ccc(O)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.82
MAPT P10636 5/20 0.70
MAOB P27338 4/20 0.70
RAB9A P51151 4/20 0.70
MAOA P21397 2/20 0.70
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
CXCL12 P48061 1/20 0.70
POLB P06746 1/20 0.70
KMT2A Q03164 4/20 0.69
MEN1 O00255 3/20 0.69
CYP3A4 P08684 2/20 0.69
HSPD1 P10809 2/20 0.69
HSPE1 P61604 2/20 0.69
CYP1B1 Q16678 2/20 0.69
PKM P14618 1/20 0.69
NFKB1 P19838 1/20 0.69
NFKB2 Q00653 1/20 0.69
RELA Q04206 1/20 0.69
ALDH2 P05091 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787169 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL773589 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
SCHEMBL25236411 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL25202156 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
SCHEMBL10703657 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
SCHEMBL25223420 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
SCHEMBL25211913 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL773588 0.91 F3 (1.00) F3MAPTMAOBRAB9AMAOA
SCHEMBL8663994 0.86 CYP1B1 (0.72) F3MAPTMAOBRAB9AMAOA
SCHEMBL10891530 0.86 CYP1B1 (0.72) F3MAPTMAOBRAB9AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B F3 5/4885MAPT 3297/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.