Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | MAOB | P27338 | 5/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.70 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548040 | 1.00 | MAPT (1.00) | MAPTMAOBMAOARAB9APOLB | |
| SCHEMBL548041 | 1.00 | MAPT (1.00) | MAPTMAOBMAOARAB9APOLB | |
| SCHEMBL8965069 | 1.00 | MAPT (1.00) | MAPTMAOBMAOARAB9APOLB | |
| 4,4'-Dimethylchalcone SCHEMBL979560 | 0.93 | MAPT (1.00) | MAPTMAOBMAOARAB9APOLB | |
| 4,4'-Dimethylchalcone SCHEMBL979559 | 0.93 | MAPT (1.00) | MAPTMAOBMAOARAB9APOLB | |
| SCHEMBL25236411 | 0.91 | F3 (1.00) | MAPTMAOBMAOARAB9APOLB | |
| SCHEMBL25223420 | 0.91 | F3 (1.00) | MAPTMAOBMAOARAB9APOLB | |
| SCHEMBL25211913 | 0.91 | F3 (1.00) | MAPTMAOBMAOARAB9APOLB | |
| 4,4'-Dihydroxychalcone SCHEMBL773588 | 0.91 | F3 (1.00) | MAPTMAOBMAOARAB9APOLB | |
| 4,4'-Dihydroxychalcone SCHEMBL25202156 | 0.91 | F3 (1.00) | MAPTMAOBMAOARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | claimed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | claimed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | claimed |
| CN-116217461-B | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-116283789-B | Pyridazine-containing chalcone derivative and preparation method and application thereof | 贵州大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-116120256-B | Chalcone compound containing thiazole oxime ether and preparation method and application thereof | 贵州大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117343024-A | Chalcone derivative containing benzoxazole structure and preparation method and application thereof | 贵州大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116283789-A | Pyridazine-containing chalcone derivative and preparation method and application thereof | 贵州大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116217461-A | Chalcone derivative containing indole structure and preparation method and application thereof | 贵州大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-116120256-A | Chalcone compound containing thiazole oxime ether and preparation method and application thereof | 贵州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114085199-B | Chalcone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-109293616-B | Coumarin-containing chalcone derivatives, and preparation method and application thereof | 贵州大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114085199-A | Chalcone derivative containing sulfonyl piperazine and preparation method and application thereof | 贵州大学 | 2022-02-25 | — | — | CN | disclosed |
| US-5525457-A | Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |